Disease Research Trackerfrom CloudDots
metabolic

MASH / NASH

Is the science moving here?

Publications down -8.3% · Clinical trials up +41.7% as of 2026-03 provisional settling

Advocacy: Fatty Liver Foundation

Publications: 240 in 2026-03. -8.3% share of all MeSH-indexed PubMed records vs the same month last year (267 in 2025-03).
PublicationsPubMed
2402026-03
-8.3% share of all MeSH-indexed PubMed records vs same month last year (267 in 2025-03) provisional settling
0.21% share

The most recent PubMed months are still being indexed. This number will change as they settle.

Counts PubMed records indexed under this disease's MeSH heading, by the month each record was published, as a share of all MeSH-indexed PubMed records that month. MeSH indexing lags about 5 months behind publication; the newest months are still filling in.
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Clinical trials: 17 in 2026-08. +41.7% vs the same month last year (12 in 2025-08).
Clinical trialsClinicalTrials.gov
172026-08
+41.7% vs same month last year (12 in 2025-08)
Counts clinical trials newly registered on ClinicalTrials.gov, by the date each registration was first posted. Scope is global, with no country filter.
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NIH grants: 1 in 2026-08. No percentage shown. No percentage shown: both months are under 15 records. The count is ranked in its own history instead. NIH grants: latest count 1 is in the 73rd percentile, running high, versus 15-mo window (2025 to 2026) (provisional, short baseline).
NIH grantsNIH RePORTER
12026-08
73rd percentilerunning high, versus 15-mo window (2025 to 2026)low volume
Counts NIH awards whose award notice is dated in the month, from NIH RePORTER, matched on the project text. Awards cluster at the end of the federal fiscal year. Scope is the United States. No investigator or contact data is collected.
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Patents: 100 in 2026-08. No percentage shown. No percentage shown: fewer than 24 months on record. The count is ranked in the history held. Patents: latest count 100 is in the 87th percentile, running high, versus 15-mo window (2025 to 2026) (provisional, short baseline).
PatentsPatentsView / USPTO
1002026-08
87th percentilerunning high, versus 15-mo window (2025 to 2026)short history
Counts US pre-grant patent applications in the CPC classes mapped to this disease, by the date each application was published, as a share of all US pre-grant applications published that month. A publication reflects a filing about 18 months earlier. The CPC classes are broader than a single disease.
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Preprints: 17 in 2026-08. No percentage shown. No percentage shown: fewer than 24 months on record. The count is ranked in the history held. Preprints: latest count 17 is in the 10th percentile, running low, versus 15-mo window (2025 to 2026) (provisional, short baseline).
PreprintsmedRxiv / bioRxiv
172026-08
10th percentilerunning low, versus 15-mo window (2025 to 2026)short history
Counts new medRxiv and bioRxiv preprints whose title or abstract matches this disease, by posting date, deduplicated across the two servers. History starts at each server's first paper, 2013 for bioRxiv and 2019 for medRxiv. Scope is global. The only author detail kept is the corresponding author's institution.
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How unusual is this?

Each signal's latest reading ranked against this disease's own history
Publications
Publications: latest count 240 is in the 71st percentile, running high, versus 320 months since 2000.
Clinical trials
Clinical trials: latest count 17 is in the 92nd percentile, near its historical high, versus 315 months since 2000.
NIH grantsprovisional
NIH grants: latest count 1 is in the 73rd percentile, running high, versus 15-mo window (2025 to 2026) (provisional, short baseline).
Patentsprovisional
Patents: latest count 100 is in the 87th percentile, running high, versus 15-mo window (2025 to 2026) (provisional, short baseline).
Preprintsprovisional
Preprints: latest count 17 is in the 10th percentile, running low, versus 15-mo window (2025 to 2026) (provisional, short baseline).

Publications and Clinical trials are ranked against every month since 2000. NIH grants, Patents and Preprints are ranked against the 15 months we hold and are marked provisional until the full history is loaded.

Recent history

All five signals on a shared 2025 to 2026 window, scoped to the youngest source so each reads at a comparable scale
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Plot scoped to 2025 to 2026. True monthly spans by source: Publications 2000 to 2026 · 320 mo; Clinical trials 2000 to 2026 · 315 mo; NIH grants 2025 to 2026 · 15 mo; Patents 2025 to 2026 · 15 mo; Preprints 2025 to 2026 · 15 mo.
Publications2000 to 2026 · 320 mopeak 817/mo
Clinical trials2000 to 2026 · 315 mopeak 32/mo
NIH grants2025 to 2026 · 15 mobackfill pendingpeak 3/mo
Patents2025 to 2026 · 15 mobackfill pendingpeak 107/mo
Preprints2025 to 2026 · 15 mobackfill pendingpeak 36/mo

Plotted for 2025 to 2026. All five lines share one scale. Row labels show the full span.

Who's driving this

Top organizations behind each signal
Publications
Author institutions · 2023-07..2026-06
8% of works have an industry affiliation
  1. University of California San Diego257
  2. Inserm256
  3. Wenzhou Medical University222
  4. Shanghai Jiao Tong University216
  5. Sun Yat-sen University212
Clinical trials
Lead sponsors · 2023-09..2026-08
18% industry-led in 2026-08
  1. Assiut UniversityAcademic/other25
  2. Sohag UniversityAcademic/other11
  3. Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de BellisAcademic/other9
  4. Cairo UniversityAcademic/other9
  5. Tanta UniversityAcademic/other9
NIH grants
Funded institutions · 2025-07..2026-08
9 awards in window
  1. JOHNS HOPKINS UNIVERSITYMD · $2M · U242
  2. NEW YORK UNIVERSITY SCHOOL OF MEDICINENY · $1.7M · R012
  3. VIRGINIA COMMONWEALTH UNIVERSITYVA · $500K · U012
  4. UNIVERSITY OF CALIFORNIA, SAN DIEGOCA · $500K · U012
  5. HARRY S. TRUMAN MEMORIAL VA HOSPITALMO · $0 · IK61
Patents
Applicants · 2025-06..2026-08
  1. ELI LILLY AND COMPANY17
  2. Regeneron Pharmaceuticals, Inc.15
  3. Novartis AG13
  4. Alnylam Pharmaceuticals, Inc.11
  5. The Regents of the University of California11
Preprints
Corresponding institutions · 2025-06..2026-08
  1. University of Pennsylvania6
  2. Yunnan University5
  3. Boston University3
  4. City of Hope3
  5. Cleveland State University3
Recent trials, filings & preprints

Clinical trials

Organizations only. No person data.

Would you read a monthly digest for MASH / NASH?

We are gauging interest in a monthly summary of what moved: new publications, trials, grants, patents and preprints for MASH / NASH. Nothing is sent yet. If enough people ask, we will build it and you will hear first. Your address is used for that and nothing else, and you can ask us to remove it at any time.

How we map "MASH / NASH"

We used the following search terms for our data.

Publications (PubMed MeSH)"Non-alcoholic Fatty Liver Disease"[MeSH Terms] (exploded), counted on the month's [dp] range; heading verified live 2026-09-10
Author institutions (OpenAlex)topic T10351; search 'nonalcoholic steatohepatitis NASH MASH'
Clinical trials (ClinicalTrials.gov)ConditionSearch: nonalcoholic steatohepatitis OR NASH OR MASH OR MASLD OR nonalcoholic fatty liver disease OR metabolic dysfunction-associated steatohepatitis OR metabolic dysfunction-associated steatotic liver disease
NIH grants (RePORTER)advanced_text_search: nonalcoholic steatohepatitis NASH MASH MASLD nonalcoholic fatty liver
Patents (CPC)A61P1/16, A61P3/06, A61K31/4402 (US pre-grant applications by earliest publication date, USPTO ODP)
Preprints (medRxiv)title/abstract match across medRxiv + bioRxiv: steatohepatitis, nafld, masld, fatty liver, steatotic liver, hepatic steatosis

Data refreshed 2026-09-11.