Disease Research Trackerfrom CloudDots
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Huntington's Disease

Is the science moving here?

Publications up +13.3% as of 2026-03 provisional settling

Advocacy: CHDI Foundation

Publications: 50 in 2026-03. +13.3% share of all MeSH-indexed PubMed records vs the same month last year (45 in 2025-03).
PublicationsPubMed
502026-03
+13.3% share of all MeSH-indexed PubMed records vs same month last year (45 in 2025-03) provisional settling
0.04% share

The most recent PubMed months are still being indexed. This number will change as they settle.

Counts PubMed records indexed under this disease's MeSH heading, by the month each record was published, as a share of all MeSH-indexed PubMed records that month. MeSH indexing lags about 5 months behind publication; the newest months are still filling in.
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Clinical trials: 0 in 2026-08. No percentage shown. No percentage shown: both months are under 15 records. The count is ranked in its own history instead. Clinical trials: latest count 0 is in the 23rd percentile, running low, versus 319 months since 2000.
Clinical trialsClinicalTrials.gov
02026-08
23rd percentilerunning low, versus 319 months since 2000low volume
Counts clinical trials newly registered on ClinicalTrials.gov, by the date each registration was first posted. Scope is global, with no country filter.
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NIH grants: 33 in 2026-08. No percentage shown. No percentage shown: fewer than 24 months on record. The count is ranked in the history held. NIH grants: latest count 33 is in the 83rd percentile, running high, versus 15-mo window (2025 to 2026) (provisional, short baseline).
NIH grantsNIH RePORTER
332026-08
83rd percentilerunning high, versus 15-mo window (2025 to 2026)short history
Counts NIH awards whose award notice is dated in the month, from NIH RePORTER, matched on the project text. Awards cluster at the end of the federal fiscal year. Scope is the United States. No investigator or contact data is collected.
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Patents: 329 in 2026-08. No percentage shown. No percentage shown: fewer than 24 months on record. The count is ranked in the history held. Patents: latest count 329 is in the 90th percentile, near its historical high, versus 15-mo window (2025 to 2026) (provisional, short baseline).
PatentsPatentsView / USPTO
3292026-08
90th percentilenear its historical high, versus 15-mo window (2025 to 2026)short history
Counts US pre-grant patent applications in the CPC classes mapped to this disease, by the date each application was published, as a share of all US pre-grant applications published that month. A publication reflects a filing about 18 months earlier. The CPC classes are broader than a single disease.
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Preprints: 13 in 2026-08. No percentage shown. No percentage shown: both months are under 15 records. The count is ranked in its own history instead. Preprints: latest count 13 is in the 70th percentile, running high, versus 15-mo window (2025 to 2026) (provisional, short baseline).
PreprintsmedRxiv / bioRxiv
132026-08
70th percentilerunning high, versus 15-mo window (2025 to 2026)low volume
Counts new medRxiv and bioRxiv preprints whose title or abstract matches this disease, by posting date, deduplicated across the two servers. History starts at each server's first paper, 2013 for bioRxiv and 2019 for medRxiv. Scope is global. The only author detail kept is the corresponding author's institution.
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How unusual is this?

Each signal's latest reading ranked against this disease's own history
Publications
Publications: latest count 50 is in the 60th percentile, in its typical range, versus 320 months since 2000.
Clinical trials
Clinical trials: latest count 0 is in the 23rd percentile, running low, versus 319 months since 2000.
NIH grantsprovisional
NIH grants: latest count 33 is in the 83rd percentile, running high, versus 15-mo window (2025 to 2026) (provisional, short baseline).
Patentsprovisional
Patents: latest count 329 is in the 90th percentile, near its historical high, versus 15-mo window (2025 to 2026) (provisional, short baseline).
Preprintsprovisional
Preprints: latest count 13 is in the 70th percentile, running high, versus 15-mo window (2025 to 2026) (provisional, short baseline).

Publications and Clinical trials are ranked against every month since 2000. NIH grants, Patents and Preprints are ranked against the 15 months we hold and are marked provisional until the full history is loaded.

Recent history

All five signals on a shared 2025 to 2026 window, scoped to the youngest source so each reads at a comparable scale
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Plot scoped to 2025 to 2026. True monthly spans by source: Publications 2000 to 2026 · 320 mo; Clinical trials 2000 to 2026 · 319 mo; NIH grants 2025 to 2026 · 15 mo; Patents 2025 to 2026 · 15 mo; Preprints 2025 to 2026 · 15 mo.
Publications2000 to 2026 · 320 mopeak 179/mo
Clinical trials2000 to 2026 · 319 mopeak 6/mo
NIH grants2025 to 2026 · 15 mobackfill pendingpeak 40/mo
Patents2025 to 2026 · 15 mobackfill pendingpeak 378/mo
Preprints2025 to 2026 · 15 mobackfill pendingpeak 18/mo

Plotted for 2025 to 2026. All five lines share one scale. Row labels show the full span.

Who's driving this

Top organizations behind each signal
Publications
Author institutions · 2023-07..2026-06
14% of works have an industry affiliation
  1. University College London235
  2. Inserm180
  3. National Hospital for Neurology and Neurosurgery132
  4. Centre National de la Recherche Scientifique131
  5. Sorbonne Université83
Clinical trials
Lead sponsors · 2023-09..2026-08
  1. ExoRNA BioscienceIndustry3
  2. Hoffmann-La RocheIndustry3
  3. Luye Pharma Group Ltd.Industry3
  4. Skyhawk Therapeutics, Inc.Industry3
  5. University Hospital, AngersGov3
NIH grants
Funded institutions · 2025-06..2026-08
325 awards in window
  1. JOHNS HOPKINS UNIVERSITYMD · $9.5M · R01/F3117
  2. UNIVERSITY OF CALIFORNIA BERKELEYCA · $14M · U19/R0115
  3. MASSACHUSETTS GENERAL HOSPITALMA · $16.2M · R01/U0113
  4. UNIVERSITY OF SOUTHERN CALIFORNIACA · $10.6M · P01/R0112
  5. COLUMBIA UNIVERSITY HEALTH SCIENCESNY · $5.3M · F31/R379
Patents
Applicants · 2025-06..2026-08
  1. The Regents of the University of California73
  2. Ionis Pharmaceuticals, Inc.45
  3. Alnylam Pharmaceuticals, Inc.41
  4. University of Massachusetts39
  5. Regeneron Pharmaceuticals, Inc.29
Preprints
Corresponding institutions · 2025-06..2026-08
  1. Monash University5
  2. Cardiff University3
  3. Massachusetts General Hospital3
  4. University of Antwerp3
  5. University of Toronto3
Recent trials, filings & preprints

Clinical trials

Patents

Organizations only. No person data.

Would you read a monthly digest for Huntington's Disease?

We are gauging interest in a monthly summary of what moved: new publications, trials, grants, patents and preprints for Huntington's Disease. Nothing is sent yet. If enough people ask, we will build it and you will hear first. Your address is used for that and nothing else, and you can ask us to remove it at any time.

How we map "Huntington's Disease"

We used the following search terms for our data.

Publications (PubMed MeSH)"Huntington Disease"[MeSH Terms] (exploded), counted on the month's [dp] range; heading verified live 2026-09-10
Author institutions (OpenAlex)topic T10949; search 'Huntington disease'
Clinical trials (ClinicalTrials.gov)ConditionSearch: Huntington Disease OR Huntington's Disease OR Huntington's Chorea
NIH grants (RePORTER)advanced_text_search: Huntington disease OR Huntington's disease
Patents (CPC)A61P25/28, C12N15/113, A61K48/00 (US pre-grant applications by earliest publication date, USPTO ODP)
Preprints (medRxiv)title/abstract match across medRxiv + bioRxiv: huntington

Data refreshed 2026-09-11.