Publications: 140 in 2026-03. +12.4% share of all MeSH-indexed PubMed records vs the same month last year (127 in 2025-03).
PublicationsPubMed
1402026-03
+12.4% share of all MeSH-indexed PubMed records vs same month last year (127 in 2025-03)provisional · settling
0.12% share
The most recent PubMed months are still being indexed. This number will change as they settle.
Counts PubMed records indexed under this disease's MeSH heading, by the month each record was published, as a share of all MeSH-indexed PubMed records that month. MeSH indexing lags about 5 months behind publication; the newest months are still filling in.
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Clinical trials: 3 in 2026-08. No percentage shown. No percentage shown: both months are under 15 records. The count is ranked in its own history instead. Clinical trials: latest count 3 is in the 43rd percentile, in its typical range, versus 319 months since 2000.
Clinical trialsClinicalTrials.gov
32026-08
43rd percentilein its typical range, versus 319 months since 2000low volume
Counts clinical trials newly registered on ClinicalTrials.gov, by the date each registration was first posted. Scope is global, with no country filter.
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NIH grants: 80 in 2026-08. No percentage shown. No percentage shown: fewer than 24 months on record. The count is ranked in the history held. NIH grants: latest count 80 is in the 90th percentile, near its historical high, versus 15-mo window (2025 to 2026) (provisional, short baseline).
NIH grantsNIH RePORTER
802026-08
90th percentilenear its historical high, versus 15-mo window (2025 to 2026)short history
Counts NIH awards whose award notice is dated in the month, from NIH RePORTER, matched on the project text. Awards cluster at the end of the federal fiscal year. Scope is the United States. No investigator or contact data is collected.
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Patents: 312 in 2026-08. No percentage shown. No percentage shown: fewer than 24 months on record. The count is ranked in the history held. Patents: latest count 312 is in the 90th percentile, near its historical high, versus 15-mo window (2025 to 2026) (provisional, short baseline).
PatentsPatentsView / USPTO
3122026-08
90th percentilenear its historical high, versus 15-mo window (2025 to 2026)short history
Counts US pre-grant patent applications in the CPC classes mapped to this disease, by the date each application was published, as a share of all US pre-grant applications published that month. A publication reflects a filing about 18 months earlier. The CPC classes are broader than a single disease.
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Preprints: 27 in 2026-08. No percentage shown. No percentage shown: fewer than 24 months on record. The count is ranked in the history held. Preprints: latest count 27 is in the 37th percentile, in its typical range, versus 15-mo window (2025 to 2026) (provisional, short baseline).
PreprintsmedRxiv / bioRxiv
272026-08
37th percentilein its typical range, versus 15-mo window (2025 to 2026)short history
Counts new medRxiv and bioRxiv preprints whose title or abstract matches this disease, by posting date, deduplicated across the two servers. History starts at each server's first paper, 2013 for bioRxiv and 2019 for medRxiv. Scope is global. The only author detail kept is the corresponding author's institution.
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How unusual is this?
Each signal's latest reading ranked against this disease's own history
Publications
Publications: latest count 140 is in the 69th percentile, in its typical range, versus 320 months since 2000.
69thpercentile
in its typical range
140/mo · higher than 68% of 320 months since 2000
Clinical trials
Clinical trials: latest count 3 is in the 43rd percentile, in its typical range, versus 319 months since 2000.
43rdpercentile
in its typical range
3/mo · higher than 39% of 319 months since 2000
NIH grantsprovisional
NIH grants: latest count 80 is in the 90th percentile, near its historical high, versus 15-mo window (2025 to 2026) (provisional, short baseline).
90thpercentile
near its historical high
80/mo · higher than 87% of 15-mo window (2025 to 2026)
Patentsprovisional
Patents: latest count 312 is in the 90th percentile, near its historical high, versus 15-mo window (2025 to 2026) (provisional, short baseline).
90thpercentile
near its historical high
312/mo · higher than 87% of 15-mo window (2025 to 2026)
Preprintsprovisional
Preprints: latest count 27 is in the 37th percentile, in its typical range, versus 15-mo window (2025 to 2026) (provisional, short baseline).
37thpercentile
in its typical range
27/mo · higher than 20% of 15-mo window (2025 to 2026)
Publications and Clinical trials are ranked against every month since 2000. NIH grants, Patents and Preprints are ranked against the 15 months we hold and are marked provisional until the full history is loaded.
Recent history
All five signals on a shared 2025 to 2026 window, scoped to the youngest source so each reads at a comparable scaleDownload ▾
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Plot scoped to 2025 to 2026. True monthly spans by source: Publications 2000 to 2026 · 320 mo; Clinical trials 2000 to 2026 · 319 mo; NIH grants 2025 to 2026 · 15 mo; Patents 2025 to 2026 · 15 mo; Preprints 2025 to 2026 · 15 mo.
Publications2000 to 2026 · 320 mopeak 299/mo
Clinical trials2000 to 2026 · 319 mopeak 17/mo
NIH grants2025 to 2026 · 15 mobackfill pendingpeak 94/mo
Patents2025 to 2026 · 15 mobackfill pendingpeak 358/mo
Preprints2025 to 2026 · 15 mobackfill pendingpeak 42/mo
Plotted for 2025 to 2026. All five lines share one scale. Row labels show the full span.
Who's driving this
Top organizations behind each signal
Publications
Author institutions · 2023-07..2026-06
11%of works have an industry affiliation
German Center for Neurodegenerative Diseases166
Inserm159
University College London157
Massachusetts General Hospital125
University of Sheffield107
Clinical trials
Lead sponsors · 2023-09..2026-08
33%industry-led in 2026-08
Novartis PharmaceuticalsIndustry9
n-Lorem FoundationAcademic/other7
Assistance Publique - Hôpitaux de ParisAcademic/other6
BiogenIndustry6
Istituto Auxologico ItalianoAcademic/other6
NIH grants
Funded institutions · 2025-06..2026-08
601awards in window
COLUMBIA UNIVERSITY HEALTH SCIENCESNY · $19.5M · R01/F3131
JOHNS HOPKINS UNIVERSITYMD · $17.8M · R01/F3129
MASSACHUSETTS GENERAL HOSPITALMA · $50.4M · U01/R0118
WASHINGTON UNIVERSITYMO · $9.9M · R01/F3118
UNIV OF MASSACHUSETTS MED SCH WORCESTERMA · $11.3M · R01/R2117
Patents
Applicants · 2025-06..2026-08
The Regents of the University of California66
Ionis Pharmaceuticals, Inc.43
Alnylam Pharmaceuticals, Inc.38
University of Massachusetts33
Hoffmann-La Roche Inc.26
Preprints
Corresponding institutions · 2025-06..2026-08
King's College London10
University of Pennsylvania7
Stanford University6
Liangzhu Laboratory, Zhejiang University School of Medicine, Hangzhou, 310000, China; Regenerative Bio Inc., Hangzhou, Zhejiang, China5
2026-08-25medrxivDepartment of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
Organizations only. No person data.
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We are gauging interest in a monthly summary of what moved: new publications, trials, grants, patents and preprints for Amyotrophic Lateral Sclerosis (ALS). Nothing is sent yet. If enough people ask, we will build it and you will hear first. Your address is used for that and nothing else, and you can ask us to remove it at any time.
Noted. Thanks for the interest in Amyotrophic Lateral Sclerosis (ALS).
How we map "Amyotrophic Lateral Sclerosis (ALS)"
We used the following search terms for our data.
Publications (PubMed MeSH)
"Amyotrophic Lateral Sclerosis"[MeSH Terms] (exploded), counted on the month's [dp] range; heading verified live 2026-09-10